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Analysis of Common SNPs across Continents Reveals Major Genomic Differences between Human Populations.

Genes - 18 Aug 2022

Fedorova Larisa, Khrunin Andrey, Khvorykh Gennady, Lim Jan, Thornton Nicholas, Mulyar Oleh A, Limborska Svetlana, Fedorov Alexei

Abstract excerpt

Common alleles tend to be more ancient than rare alleles. These common SNPs appeared thousands of years ago and reflect intricate human evolution including various adaptations, admixtures, and migration events. Eighty-four thousand abundant region-specific alleles (ARSAs) that are common in one continent but absent in the rest of the world have been characterized by processing 3100 genomes from 230 populations....

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PMID: 36011383
DOI: 10.3390/genes13081472
PMCID: PMC9408407

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