Article
Long Non-Coding RNA H19 Prevents Lens Fibrosis through Maintaining Lens Epithelial Cell Phenotypes.
Cells - 17 Aug 2022
Xiong Lang, Sun Yan, Huang Jingqi, Ma Pengjuan, Wang Xiaoran, Wang Jiani, Chen Baoxin, Chen Jieping, Huang Mi, Huang Shan, Liu Yizhi
Abstract excerpt
The integrity of lens epithelial cells (LECs) lays the foundation for lens function and transparency. By contrast, epithelial-mesenchymal transition (EMT) of LECs leads to lens fibrosis, such as anterior subcapsular cataracts (ASC) and fibrotic forms of posterior capsule opacification (PCO). However, the underlying mechanisms remain unclear. Here, we aimed to explore the role of long non-coding RNA (lncRNA) H19...
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