Article
Real-World Testing Practices, Treatment Patterns and Clinical Outcomes in Patients from Central Eastern Europe with EGFR-Mutated Advanced Non-Small Cell Lung Cancer: A Retrospective Chart Review Study (REFLECT).
Current oncology (Toronto, Ont.) - 17 Aug 2022
Janžič Urška, Turnšek Nina, Dediu Mircea, Donev Ivan Shterev, Lupu Roxana, Teodorescu Gabriela, Ciuleanu Tudor E, Pluzanski Adam
Abstract excerpt
The targeted therapy with tyrosine kinase inhibitors (TKIs) against the epidermal growth factor receptor mutation (EGFRm) in advanced non-small cell lung cancer (NSCLC) changed the treatment paradigm. REFLECT study (NCT04031898) explored EGFR/T790M testing and treatment patterns in EGFRm NSCLC patients receiving first- or second-generation (1G/2G) EGFR TKIs as front-line (1L) in eight countries. Pooled data from...
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