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A novel long noncoding RNA SP100-AS1 induces radioresistance of colorectal cancer via sponging miR-622 and stabilizing ATG3

17 Aug 2022

Abstract excerpt

Although radiotherapy is an essential modality in the treatment of colorectal cancer (CRC), the incidence of radioresistance remains high clinically. Long noncoding RNAs (lncRNAs) reportedly play critical roles in CRC radioresistance by regulating genes or proteins at the transcriptional or post-translational levels. This study aimed to identify novel lncRNAs involved in radioresistance. We found that SP100-AS1...

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Cancer-related molecular mechanisms research
Circular RNAs in diseases
Mycobacterium research and diagnosis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35978049
DOI: 10.1038/s41418-022-01049-1

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