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Article

Causal association of juvenile idiopathic arthritis-associated uveitis with depression and anxiety: a bidirectional Mendelian randomization study.

International ophthalmology - 1 Feb 2023

Zhang Jun, Hu Shuqiong, Luo Xiang, Huang Changwei, Cao Qingfeng

Abstract excerpt

PURPOSE: The objective of this article was to examine the potential effect of juvenile idiopathic arthritis-associated uveitis (JIAU) on the risk of major depressive and anxiety disorders through Mendelian randomization (MR) study. METHODS: Genetic instrumental variables from the largest available genome-wide association study for JIAU, major depressive disorder, and anxiety disorder were applied. A set of...

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PMID: 35947254
DOI: 10.1007/s10792-022-02462-8

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