Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Precision therapy with quinidine of KCNT1-related epileptic disorders: A systematic review.

British journal of clinical pharmacology - 1 Dec 2022

Xu Da, Chen Shuang, Yang Jun, Wang Xiufeng, Fang Zhi, Li Man

Abstract excerpt

AIMS: Despite numerous studies on quinidine therapies for epilepsies associated with KCNT1 gene mutations, there is no consensus on its clinical utility. Thus, we reviewed studies evaluating the efficacy and safety of quinidine in KCNT1-related epileptic disorders. METHODS: Electronic databases were queried for in vivo and in vitro studies on quinidine therapy in KCNT1-related epilepsies published on or before 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticonvulsants
Share to Epilepsy
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nerve Tissue Proteins

Share to Potassium Channels, Sodium-Activated

Share to Quinidine

Share to Seizures

Source

Identifiers

PMID: 35940594
DOI: 10.1111/bcp.15479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Precision therapy with quinidine of KCNT1-related epileptic disorders: A systematic review.PMID 35940594Read ↗

New use for an old drug: quinidine in KCNT1-related epilepsy therapy.Semantic proximity Read ↗

Quinidine Therapy for Lennox-Gastaut Syndrome With KCNT1 Mutation. A Case Report and Literature ReviewSemantic proximity Read ↗

Quinidine therapy for West syndrome with KCNTI mutation: A case report.Semantic proximity Read ↗

Personalized medicine in genetic epilepsies - possibilities, challenges, and new frontiers.Semantic proximity Read ↗

Approaches for the discovery of drugs that target K Na 1.1 channels in KCNT1-associated epilepsy.Semantic proximity Read ↗

KCNT2-Related Disorders: Phenotypes, Functional, and Pharmacological Properties.Semantic proximity Read ↗

Potassium channels and epilepsy.Semantic proximity Read ↗

KCNT1 gain of function in 2 epilepsy phenotypes is reversed by quinidine.Semantic proximity Read ↗

Targeting KNa1.1 channels in KCNT1-associated epilepsy.Semantic proximity Read ↗

Therapeutic Drug Monitoring of Quinidine in Pediatric Patients with KCNT1 Genetic VariantsSemantic proximity Read ↗

Quinidine in the treatment of KCNT1-positive epilepsies.Semantic proximity Read ↗

Characterizing the Clinical and Genetic Landscape of <i>KCNT1</i> -Related DisordersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.