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Contrasting Patterns in the Early Stage of SARS-CoV-2 Evolution between Humans and Minks.

Molecular biology and evolution - 1 Sept 2022

Tai Jui-Hung, Sun Hsiao-Yu, Tseng Yi-Cheng, Li Guanghao, Chang Sui-Yuan, Yeh Shiou-Hwei, Chen Pei-Jer, Chaw Shu-Miaw, Wang Hurng-Yi

Abstract excerpt

One of the unique features of SARS-CoV-2 is its apparent neutral evolution during the early pandemic (before February 2020). This contrasts with the preceding SARS-CoV epidemics, where viruses evolved adaptively. SARS-CoV-2 may exhibit a unique or adaptive feature which deviates from other coronaviruses. Alternatively, the virus may have been cryptically circulating in humans for a sufficient time to have...

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PMID: 35934827
DOI: 10.1093/molbev/msac156
PMCID: PMC9384665

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