Article
CFTR gene variants, air pollution, and childhood asthma in a California Medicaid population.
Pediatric pulmonology - 1 Nov 2022
Thilakaratne Ruwan, Graham Steve, Moua John, Jones Caitlin G, Collins Caroline, Mann Jennifer, Sciortino Stanley, Wong Jacklyn, Kharrazi Martin
Abstract excerpt
Carriers of the cystic fibrosis transmembrane conductance regulator (CFTR) gene ("carriers") have been found to have an increased risk of persistent asthma. However, it is unclear at what level of CFTR function this risk exists and whether it is modified by asthmogens, such as air pollution. We conducted a retrospective cohort study of children born in California between July 2007 and December 2013, linking CFTR...
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