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Article

Clinical, biological, radiological, and genetic study of LPAC syndrome in Tunisian patients.

Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology - 1 Aug 2022

Halleb Yosra, Ben Jazia Elhem, Akkari Imen, Zaghouani Houneida, Hmila Fahmi, Ghrissi Rafik, Saad Ali, Gribaa Moez

Abstract excerpt

BACKGROUND AND STUDY AIMS: Low phospholipid-associated cholelithiasis (LPAC) syndrome is a form of cholelithiasis associated with the ABCB4 gene mutation. The defects of the protein ABCB4 encoded by this gene promote the formation of biliary cholesterol microcalculations. ABCB4 screening is negative in a significant proportion of patients. PATIENTS AND METHODS: An analytical study of the epidemiological,...

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PMID: 35922258
DOI: 10.1016/j.ajg.2022.06.002

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