Article
Age, corticosteroid treatment and site of mutations affect motor functional changes in young boys with Duchenne Muscular Dystrophy.
PloS one - 1 Jan 2022
Coratti Giorgia, Lenkowicz Jacopo, Norcia Giulia, Lucibello Simona, Ferraroli Elisabetta, d'Amico Adele, Bello Luca, Pegoraro Elena, Messina Sonia, Ricci Federica, Mongini Tiziana, Berardinelli Angela, Masson Riccardo, Previtali Stefano C, D'angelo Grazia, Magri Francesca, Comi Giacomo P, Politano Luisa, Passamano Luigia, Vita Gianluca, Sansone Valeria A, Albamonte Emilio, Panicucci Chiara, Bruno Claudio, Pini Antonella, Bertini Enrico, Patarnello Stefano, Pane Marika, Mercuri Eugenio
Abstract excerpt
The aim of this study was to establish the possible effect of age, corticosteroid treatment and brain dystrophin involvement on motor function in young boys affected by Duchenne Muscular Dystrophy who were assessed using the North Star Ambulatory Assessment between the age of 4 and 7 years. The study includes 951 North Star assessments from 226 patients. Patients were subdivided according to age, to the site of...
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