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Article

Molecular stratification of arrhythmogenic mechanisms in the Andersen Tawil syndrome.

Cardiovascular research - 2 May 2023

Moreno-Manuel Ana Isabel, Gutiérrez Lilian K, Vera-Pedrosa María Linarejos, Cruz Francisco Miguel, Bermúdez-Jiménez Francisco José, Martínez-Carrascoso Isabel, Sánchez-Pérez Patricia, Macías Álvaro, Jalife José

Abstract excerpt

Andersen-Tawil syndrome (ATS) is a rare inheritable disease associated with loss-of-function mutations in KCNJ2, the gene coding the strong inward rectifier potassium channel Kir2.1, which forms an essential membrane protein controlling cardiac excitability. ATS is usually marked by a triad of periodic paralysis, life-threatening cardiac arrhythmias and dysmorphic features, but its expression is variable and not...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35892314
DOI: 10.1093/cvr/cvac118
PMCID: PMC10153646

Genes

KCNJ2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular stratification of arrhythmogenic mechanisms in the Andersen Tawil syndrome.PMID 35892314Read ↗

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Risk Stratification of Arrhythmogenic Consequences of Andersen-Tawil Syndrome Affecting Kir2.1-PIP2 InteractionsSemantic proximity Read ↗

Reversible Dilated Cardiomyopathy Caused by a High Burden of Ventricular Arrhythmias in Andersen-Tawil Syndrome.Semantic proximity Read ↗

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