Simultaneous quantification of 70 elements in biofluids within 5 min using inductively coupled plasma mass spectrometry to reveal elementomic phenotypes of healthy Chinese adults.

Abstract excerpt

High-throughput quantification of the composition of all chemical elements (elementome) in biological samples is essential for understanding their diverse functions in large cohort studies. We, here, established an ICP-MS method to simultaneously quantify 70 elements in 50 μL biofluids within 5 min. This validated method had excellent quantification linearity (R2 > 0.998), sensitivity (with LOD as low as...

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