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Article

Targeting the lncRNA FGD5-AS1/miR-497-5p/PD-L1 Axis Inhibits Malignant Phenotypes in Colon Cancer (CC).

BioMed research international - 1 Jan 2022

Zhang Lijuan, Cai Xinyi, Dai Youguo, Chen Yun, Yu Jing, Zhou Yongchun

Abstract excerpt

Long noncoding RNAs (lncRNAs) regulate cancer progression and drug resistance. However, the role of lncRNA FGD5-AS1 in regulating colon cancer (CC) progression is still largely unknown. Hence, this study investigated the role of lncRNA FGD5-AS1 in regulating colon cancer (CC) progression and found that lncRNA FGD5-AS1 regulated miR-497-5p/PD-L1 axis to promote cancer progression in CC cells in vitro and in vivo....

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Share to B7-H1 Antigen
Share to Cell Movement
Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colonic Neoplasms

Share to Gene Expression Regulation, Neoplastic

Share to Guanine Nucleotide Exchange Factors

Share to MicroRNAs

Share to RNA, Long Noncoding

Source

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Identifiers

PMID: 35845947
DOI: 10.1155/2022/1133332
PMCID: PMC9279048

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