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Benign SNPs in the Coding Region of TP53: Finding the Needles in a Haystack of Pathogenic Variants.

Cancer research - 4 Oct 2022

Soussi Thierry

Abstract excerpt

With the recent explosion in high-throughput genotyping technology, the amount and quality of SNP data have increased exponentially, facilitating the discovery of multiple uncommon SNPs in the human population. To provide unified and centralized resources for the scientific community, several repositories have been developed that aggregate numerous population studies and serve widely as references to filter...

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PMID: 35802772
DOI: 10.1158/0008-5472.CAN-22-0172

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