Article
[Establishment of sequence-based typing assay for KIR2DS4 gene and identification of a new allele KIR2DS4*016].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Jun 2022
Xu Yunping, Sun Liyan, He Liumei, Gao Suqing
Abstract excerpt
OBJECTIVE: To establish a reliable sequence-based typing method for KIR2DS4 and study its allele polymorphism in Chinese Han population. METHODS: Using PCR-SSP method to detect the positive or negative of KIR2DS4 gene in 222 random Chinese Han individuals, and then using the method of high fidelity and long-fragment PCR-SBT to amplify, sequence and genotype the exons 4 and 5 of KIR2DS4 positive individuals....
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