Article
A Novel Somatic Mutation of CACNA1H p.V1937M in Unilateral Primary Hyperaldosteronism.
Frontiers in endocrinology - 1 Jan 2022
Tseng Chi-Shin, Peng Kang-Yung, Wang Shuo-Meng, Tsai Yao-Chou, Huang Kuo-How, Lin Wei-Chou, Hu Ya-Hui, Wu Vin-Cent, Chueh Jeff S
Abstract excerpt
Background: Somatic mutations for excess aldosterone production have been frequently identified as important roles in the pathogenesis of unilateral primary hyperaldosteronism (uPA). Although CACNA1H mutation represents a minor etiology in primary aldosteronism, it plays a significant role in causing uPAs in sporadic cases. Objective: To identify novel somatic CACNA1H mutation in patients with uPA and investigate...
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