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The concealed side of caspases: beyond a killer of cells

1 Dec 2024

Abstract excerpt

Since the late 20th century, researchers have known that caspases are a pillar of cell death, particularly apoptosis. However, recent advances in cell biology have unraveled the multiple roles of caspases. These enzymes have an unconventional role in cell proliferation, differentiation, and invasion. As a result, caspase deregulation can fuel the fire of cancer, incite flames of inflammation, flare...

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PMID: 39625520
DOI: 10.1007/s00018-024-05495-7

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