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Article

CFTR RNA- and DNA-based therapies.

Current opinion in pharmacology - 1 Aug 2022

Harrison Patrick T

Abstract excerpt

This review provides an update on recent developments of RNA- and DNA-based methodologies and their intracellular targets in the context of cystic fibrosis (CF) lung disease. Ultimately, clinical success will require a suitable delivery system, but since the cargo for all these strategies is nucleic acid, it should hopefully be possible to exploit delivery breakthroughs from one study and apply these innovations...

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PMID: 35709547
DOI: 10.1016/j.coph.2022.102247

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