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Article

TYRP1 Protects Against the Apoptosis and Oxidative Stress of Retinal Ganglion Cells by Binding to PMEL

16 Jun 2022

Abstract excerpt

OBJECTIVES: This research aimed to dissect the function of TYRP1 and PMEL in glaucomatous animal and cell models. METHODS: A chronic ocular hypertension (COH) rat model was induced in the right eyes of rats through the electrocoagulation of superficial iris veins. In addition, an oxygen-glucose deprivation (OGD)-retinal ganglion cell (RGC) model was constructed through OGD. TYRP1 and PMEL expression was altered...

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Identifiers

PMID: 35708352
DOI: 10.1080/09273948.2022.2081862

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