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Article

The clinical utility of cfRNA for disease detection and surveillance: A proof of concept study in non-small cell lung cancer.

Thoracic cancer - 1 Aug 2022

Metzenmacher Martin, Hegedüs Balazs, Forster Jan, Schramm Alexander, Horn Peter A, Klein Christoph A, Bielefeld Nicola, Ploenes Till, Aigner Clemens, Siveke Jens T, Schuler Martin, Lueong Smiths S

Abstract excerpt

BACKGROUND: CT scans are used in routine clinical practice for the diagnosis and treatment surveillance of non-small cell lung cancer (NSCLC). However, more sensitive methods are desirable. Liquid biopsy analyses of RNA and DNA can offer more sensitive diagnostic approaches. Cell-free RNA (cfRNA) has been described in several malignancies, but its clinical utility has not previously been explored. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35708207
DOI: 10.1111/1759-7714.14540
PMCID: PMC9346179

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