Article
Genotype-genotype interactions of the OXTR gene polymorphisms are associated with self-reported daytime dysfunction, sleep latency and personal distress.
Journal of sleep research - 1 Feb 2023
Li Yuling, Wang Yuan, Guan Xin, Yue Jingyan, Wu Hanjing Emily, Zhen Shiqian, He Shu-Chang, Zhang Xiang-Yang
Abstract excerpt
The oxytocin receptors located in the corticotropin-releasing factor neurons of the paraventricular nucleus are stimulated by oxytocin. Oxytocin functions as the regulator of the corticotropin-releasing factor system and in turn promotes sleep quality. The objective of this study was to examine the main and genotype-genotype interactive effects of the oxytocin receptor gene (OXTR) polymorphisms on sleep quality....
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