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Article

Leishmania braziliensis causing human disease in Northeast Brazil presents loci with genotypes in long-term equilibrium.

PLoS neglected tropical diseases - 1 Jun 2022

Silva Juliana A, Pinheiro Ana Isabelle, Dourado Maria Luiza, Medina Lilian, Queiroz Adriano, Guimarães Luiz Henrique, Lessa Marcus Miranda, Lago Ednaldo L, Machado Paulo Roberto L, Wilson Mary E, Carvalho Edgar M, Schriefer Albert

Abstract excerpt

BACKGROUND: Leishmaniases are neglected tropical diseases that inflict great burden to poor areas of the globe. Intense research has aimed to identify parasite genetic signatures predictive of infection outcomes. Consistency of diagnostic tools based on these markers would greatly benefit from accurate understanding of Leishmania spp. population genetics. We explored two chromosomal loci to characterize a...

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PMID: 35704664
DOI: 10.1371/journal.pntd.0010390
PMCID: PMC9239440

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