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Article

Mobility test to assess functional vision in dark-adapted patients with Leber congenital amaurosis.

BMC ophthalmology - 14 Jun 2022

Roman Alejandro J, Cideciyan Artur V, Wu Vivian, Mascio Abraham A, Krishnan Arun K, Garafalo Alexandra V, Jacobson Samuel G

Abstract excerpt

BACKGROUND: Inherited retinal degenerations (IRDs) affect daylight and night vision to different degrees. In the current work, we devise a method to quantify mobility under dark-adapted conditions in patients with severe childhood blindness due to Leber congenital amaurosis (LCA). Mobility thresholds from two different LCA genotypes are compared to dark-adapted vision measurements using the full-field stimulus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35701753
DOI: 10.1186/s12886-022-02475-y
PMCID: PMC9195222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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