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Article

Reactive Oxygen Species are Essential for Placental Angiogenesis During Early Gestation

1 Jan 2022

Abstract excerpt

Background. Preeclampsia (PE) is associated with insufficient placental perfusion attributed to maldevelopment of the placental vasculature. Reactive oxygen species (ROS) are implicated in angiogenesis, but their regulatory effects and mechanisms in placental vascular development remain unclear. Methods. Placental oxidative stress was determined throughout gestation by measuring 4‐hydroxynonenal (4HNE) and...

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PMID: 35693704
DOI: 10.1155/2022/4290922

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