Article
Risk SNP-mediated LINC01614 upregulation drives head and neck squamous cell carcinoma progression via PI3K/AKT signaling pathway.
Molecular carcinogenesis - 1 Aug 2022
Hou Yaxuan, Zhou Meng, Li Yuncheng, Tian Tingting, Sun Xun, Chen Mo, Xu Wenmao, Lu Meixia
Abstract excerpt
As potential biomarkers and therapeutic targets, long noncoding RNAs (lncRNAs) are involved in the tumorigenesis of various tumors. Genetic variation in long noncoding regions can lead to lncRNA dysfunction and even cancer. Nevertheless, studies on the association between lncRNA-associated single-nucleotide polymorphisms (SNPs) and the risk of head and neck squamous cell carcinoma (HNSCC) remain inadequate. Here,...
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