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Prenatal Zinc Deficient Mice as a Model for Autism Spectrum Disorders

29 May 2022

Abstract excerpt

Epidemiological studies have shown a clear association between early life zinc deficiency and Autism Spectrum Disorders (ASD). In line with this, mouse models have revealed prenatal zinc deficiency as a profound risk factor for neurobiological and behavioral abnormalities in the offspring reminiscent of ASD behavior. From these studies, a complex pathology emerges, with alterations in the gastrointestinal and...

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PMID: 35682762
DOI: 10.3390/ijms23116082

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