PTBP2 - a gene with relevance for both Anorexia nervosa and body weight regulation.

doi:10.1038/s41398-022-02018-5

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Article

PTBP2 - a gene with relevance for both Anorexia nervosa and body weight regulation.

Translational psychiatry - 9 Jun 2022

Zheng Yiran, Rajcsanyi Luisa Sophie, Herpertz-Dahlmann Beate, Seitz Jochen, de Zwaan Martina, Herzog Wolfgang, Ehrlich Stefan, Zipfel Stephan, Giel Katrin, Egberts Karin, Burghardt Roland, Föcker Manuel, Al-Lahham Saad, Peters Triinu, Libuda Lars, Antel Jochen, Hebebrand Johannes, Hinney Anke

Abstract excerpt

Genetic factors are relevant for both eating disorders and body weight regulation. A recent genome-wide association study (GWAS) for anorexia nervosa (AN) detected eight genome-wide significant chromosomal loci. One of these loci, rs10747478, was also genome-wide and significantly associated with body mass index (BMI). The nearest coding gene is the Polypyrimidine Tract Binding Protein 2 gene (PTBP2). To detect...

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PMID: 35680849
DOI: 10.1038/s41398-022-02018-5
PMCID: PMC9184595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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