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Comprehensive analysis of the importance of PLAUR in the progression and immune microenvironment of renal clear cell carcinoma

8 Jun 2022

Abstract excerpt

Clear cell renal cell carcinoma (ccRCC) is a common type of kidney cancer with a high mortality rate, and the discovery of new therapeutic markers is essential to improve patient survival. The plasminogen activator urokinase receptor (PLAUR) plays key roles in tissue remodeling and extracellular matrix degradation, which contribute to invasion and metastasis, a major feature of tumor malignancy. The role of PLAUR...

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PMID: 35675366
DOI: 10.1371/journal.pone.0269595

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