Addition of Bevacizumab to Erlotinib as First-Line Treatment of Patients With EGFR-Mutated Advanced Nonsquamous NSCLC: The BEVERLY Multicenter Randomized Phase 3 Trial.

doi:10.1016/j.jtho.2022.05.008

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Article

Addition of Bevacizumab to Erlotinib as First-Line Treatment of Patients With EGFR-Mutated Advanced Nonsquamous NSCLC: The BEVERLY Multicenter Randomized Phase 3 Trial.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Sept 2022

Piccirillo Maria Carmela, Bonanno Laura, Garassino Marina Chiara, Esposito Giovanna, Dazzi Claudio, Cavanna Luigi, Burgio Marco Angelo, Rosetti Francesco, Rizzato Simona, Morgillo Floriana, Cinieri Saverio, Veccia Antonello, Papi Maximilan, Tonini Giuseppe, Gebbia Vittorio, Ricciardi Serena, Pozzessere Daniele, Ferro Alessandra, Proto Claudia, Costanzo Raffaele, D'Arcangelo Manolo, Proietto Manuela, Gargiulo Piera, Di Liello Raimondo, Arenare Laura, De Marinis Filippo, Crinò Lucio, Ciardiello Fortunato, Normanno Nicola, Gallo Ciro, Perrone Francesco, Gridelli Cesare, Morabito Alessandro

Abstract excerpt

INTRODUCTION: Adding bevacizumab to erlotinib prolonged progression-free survival (PFS) of patients with EGFR-mutated advanced NSCLC in the Japanese JO25567 trial, but limited data were available in non-Asian patients. BEVERLY is an Italian, multicenter, randomized, phase 3 investigating the addition of bevacizumab to erlotinib as first-line treatment of advanced EGFR-mutated NSCLC. METHODS: Eligible patients...

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PMID: 35659580
DOI: 10.1016/j.jtho.2022.05.008

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