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Article

Prevalence of risk alleles in the lysyl oxidase-like 1 gene in pseudoexfoliation glaucoma patients in India.

Indian journal of ophthalmology - 1 Jun 2022

Vallabh Neeru A, Sambare Chitra, Muszynska-Lyons Dorota, Patiyal Sagarika, Kelkar Aditya, Killedar Milind, Malani Sangeeta, Prabhudesai Medha, Walimbe Tejaswini, McKay Gareth J, Willoughby Colin E

Abstract excerpt

Purpose: The purpose of this study was to genotype two previously identified SNPs (rs1048661:R141L, and rs3825942:G153D) in the lysyl oxidase-like 1 (LOXL1) gene and determine their association with pseudoexfoliation glaucoma (XFG) in patients from Pune, India. Methods: All subjects underwent detailed phenotyping, and DNA extraction was performed on blood samples by using standardized techniques. Exon 1 of the...

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PMID: 35647973
DOI: 10.4103/ijo.IJO_2664_21
PMCID: PMC9359290

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