Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical validation of engineered CRISPR/Cas12a for rapid SARS-CoV-2 detection

12 Jan 2022

Abstract excerpt

Background: The coronavirus disease (COVID-19) caused by SARS-CoV-2 has swept through the globe at an unprecedented rate. CRISPR-based detection technologies have emerged as a rapid and affordable platform that can shape the future of diagnostics. Methods: We developed ENHANCEv2 that is composed of a chimeric guide RNA, a modified LbCas12a enzyme, and a dual reporter construct to improve the previously reported...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biosensors and Analytical Detection
Share to CRISPR and Genetic Engineering
Share to SARS-CoV-2 detection and testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35603267
DOI: 10.1038/s43856-021-00066-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical validation of engineered CRISPR/Cas12a for rapid SARS-CoV-2 detectionPMID 35603267Read ↗

CRISPR-cas13 enzymology rapidly detects SARS-CoV-2 fragments in a clinical settingSemantic proximity Read ↗

Advancing CRISPR-Based Solutions for COVID-19 Diagnosis and TherapeuticsSemantic proximity Read ↗

A Multiplexed Cas13-Based Assay with Point-of-Care Attributes for Simultaneous COVID-19 Diagnosis and Variant SurveillanceSemantic proximity Read ↗

Ultrasensitive and visual detection of SARS-CoV-2 using all-in-one dual CRISPR-Cas12a assaySemantic proximity Read ↗

Rapid detection of SARS-CoV-2 with CRISPR-Cas12aSemantic proximity Read ↗

Detection of Infectious Viruses Using CRISPR-Cas12-Based AssaySemantic proximity Read ↗

Evaluation of a Lyophilized CRISPR-Cas12 Assay for a Sensitive, Specific, and Rapid Detection of SARS-CoV-2Semantic proximity Read ↗

An engineered CRISPR-Cas12a variant and DNA-RNA hybrid guides enable robust and rapid COVID-19 testing.Semantic proximity Read ↗

An improved, simple and field-deployable CRISPR-Cas12a assay for the detection of SARS-CoV-2Semantic proximity Read ↗

Rapid Detection of SARS-CoV-2 Based on the LAMP Assay Associated with the CRISPRCas12a SystemSemantic proximity Read ↗

CRISPR-based biosensing systems: a way to rapidly diagnose COVID-19Semantic proximity Read ↗

A multiplexed Cas13-based assay with point-of-care attributes for simultaneous COVID-19 diagnosis and variant surveillanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.