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Genetic and phenotypic analysis of the causal relationship between aging and COVID-19

5 Oct 2021

Abstract excerpt

Background: Epidemiological studies revealed that the elderly and those with comorbidities are most affected by COVID-19, but it is important to investigate shared genetic mechanisms between COVID-19 risk and aging. Methods: We conducted a multi-instrument Mendelian Randomization analysis of multiple lifespan-related traits and COVID-19. Aging clock models were applied to the subjects with different COVID-19...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35602207
DOI: 10.1038/s43856-021-00033-z

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