Article
Identifying Circulating Tumor DNA Mutations Associated with Neoadjuvant Chemotherapy Efficacy in Local Advanced Breast Cancer.
Applied biochemistry and biotechnology - 1 Sept 2022
Wei Benjie, Shan Yanhong, Du Zhaoli, Yin Chunxia, Zhang Qianqian, Lin Haifeng, Zhang Guirong, Song Dong, Zuo Hongbin
Abstract excerpt
Circulating tumor DNA (ctDNA) correlates with tumor burden and provides early detection of treatment response and tumor genetic alterations in breast cancer. Neoadjuvant chemotherapy (NACT) has become standard therapy for local advanced breast cancer (LABC). The aim of our study was to investigate plasma ctDNA as a prognostic marker for outcome in patients with LABC treated with NACT. A total of 56 patients with...
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