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microRNA-324-3p suppresses the aggressive ovarian cancer by targeting WNK2/RAS pathway

2 May 2022

Abstract excerpt

Ovarian cancer (OC) has the highest mortality rate among gynecological cancers, which progresses owing to dysregulated microRNAs (miRNAs) expression. Our study attempts to reveal the mechanism by which decreased miR-324-3p expression suppresses OC proliferation. Quantitative real-time PCR, western blotting, in situ hybridization, and immunohistochemistry were performed to estimate miR-324-3p and WNK2 expression...

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PMID: 35549643
DOI: 10.1080/21655979.2022.2056314

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