Environmentally relevant manganese concentrations evoke anxiety phenotypes in adult zebrafish.

Abstract excerpt

Manganese (Mn) is an essential metal for living organisms. However, the excess of Mn can be toxic, especially for the central nervous system. Herein, we used adult zebrafish as model organism to investigate the relationship of an environmentally relevant Mn exposure with the onset of neurobehavioral disturbances and brain biochemical alterations. Fish were exposed to MnCl2 at 0.5, 2.0, 7.5 and 15.0 mg/L for 96 h,...

Topics

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• Acetylcholinesterase
• Anxiety
• Behavior, Animal
• Hydrocortisone
• Manganese