Article
The diagnostic importance of pathogenic variants and variant coexistence determined by NGS-based liquid biopsy approach in patients with lung adenocarcinoma.
Molecular and cellular probes - 1 Aug 2022
Cine Naci, Ali Sen Emin, Demir Gulhan, Gokbayrak Merve, Guzdolu Eda, Sertdemir Nilufer, Aydin Duygu, Kurtas Omer, Reka Seda, Sunnetci-Akkoyunlu Deniz, Eren-Keskin Seda, Uygun Kazim, Cabuk Devrim, Gorkem Aksu Maksut, Zafer Canturk Nuh, Savli Hakan
Abstract excerpt
BACKROUND: Identification of driver mutations and rapid detection of genetic changes in lung cancer are critical in the management of the disease. Genetic structures of tumor tissues tend to change constantly and the possibility of emergence of new pathogenic variants that will create resistance to treatment. Liquid biopsy analysis has been one of the most effective approaches used to monitor and identify...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.