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Article

Mitochondrial stroke-like episodes: The search for new therapies.

Pharmacological research - 1 Jun 2022

Orsucci Daniele, Caldarazzo Ienco Elena, Montano Vincenzo, Siciliano Gabriele, Mancuso Michelangelo

Abstract excerpt

A mitochondrial stroke-like event is an evolving subacute neurological syndrome linked to seizure activity and focal metabolic brain derangement in a genetically determined mitochondrial disorder. The acronym "MELAS" (mitochondrial encephalopathy associated with lactic acidosis and stroke-like lesions) identifies subjects with molecular, biochemical and/or histological evidence of mitochondrial disorder who...

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PMID: 35462010
DOI: 10.1016/j.phrs.2022.106228

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