Article
Optical Genome Mapping and Single Nucleotide Polymorphism Microarray: An Integrated Approach for Investigating Products of Conception.
Genes - 3 Apr 2022
Sahajpal Nikhil Shri, Mondal Ashis K, Ananth Sudha, Pundkar Chetan, Jones Kimya, Williams Colin, Fee Timothy, Weissman Amanda, Tripodi Giuseppe, Oza Eesha, Gavrilova-Jordan Larisa, Omar Nivin, Hastie Alex R, DuPont Barbara R, Layman Lawrence, Chaubey Alka, Kolhe Ravindra
Abstract excerpt
Conventional cytogenetic analysis of products of conception (POC) is of limited utility because of failed cultures, as well as microbial and maternal cell contamination (MCC). Optical genome mapping (OGM) is an emerging technology that has the potential to replace conventional cytogenetic methods. The use of OGM precludes the requirement for culturing (and related microbial contamination). However, a high...
Topics
Join the communities discussing this publication.