Article
Surgical management of abdominal desmoids: a systematic review and meta-analysis.
Irish journal of medical science - 1 Apr 2023
Moore Dave, Burns Lucy, Creavin Ben, Ryan Eanna, Conlon Kevin, Kelly Michael Eamon, Kavanagh Dara
Abstract excerpt
BACKGROUND: Desmoid tumours are benign fibromatous tumours arising from dysregulated myofibroblast proliferation within musculoaponeurotic structures. They can occur sporadically but more commonly are associated with genetic syndromes such as familial adenomatous polyposis (Sakorafas et al. in Surg Oncol 16(2):131-142, 2007) (FAP). Mutations in either the Wnt, β-catenin or APC genes are 'key' triggers for the...
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