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Evidence for local and international spread of Mycobacterium avium subspecies paratuberculosis through whole genome sequencing of isolates from the island of Ireland.

Veterinary microbiology - 1 May 2022

Perets Viktor, Allen Adrian, Crispell Joseph, Cassidy Sophie, O'Connor Aoife, Farrell Damien, Browne John A, O'Mahony Jim, Skuce Robin, Kenny Kevin, Gordon Stephen V

Abstract excerpt

We describe application of whole genome sequencing (WGS) to a collection of 197 Mycobacterium avium subsp paratuberculosis (MAP) isolates gathered from 122 cattle herds across 27 counties of the island of Ireland. We compare WGS to MAP diversity quantified using mycobacterial interspersed random unit - variable number tandem repeats (MIRU-VNTR). While MIRU-VNTR showed only two major types, WGS could split the 197...

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PMID: 35405477
DOI: 10.1016/j.vetmic.2022.109416

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