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Metagenomic Identification of Microbial Signatures Predicting Pancreatic Cancer From a Multinational Study

8 Apr 2022

Abstract excerpt

BACKGROUND & AIMS: To identify gut and oral metagenomic signatures that accurately predict pancreatic ductal carcinoma (PDAC) and to validate these signatures in independent cohorts. METHODS: We conducted a multinational study and performed shotgun metagenomic analysis of fecal and salivary samples collected from patients with treatment-naïve PDAC and non-PDAC controls in Japan, Spain, and Germany. Taxonomic and...

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PMID: 35398347
DOI: 10.1053/j.gastro.2022.03.054

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