Article
An overview of SNP-SNP microhaplotypes in the 26 populations of the 1000 Genomes Project.
International journal of legal medicine - 1 Sept 2022
Xue Jiaming, Qu Shengqiu, Tan Mengyu, Xiao Yuanyuan, Zhang Ranran, Chen Dezhi, Lv Meili, Zhang Yiming, Zhang Lin, Liang Weibo
Abstract excerpt
Microhaplotypes (MHs) are a promising new type of forensic markers that are defined by the combinations of two- or more single-nucleotide polymorphisms (SNPs) within 200 bp. Their advantages, such as low mutation rates, lack of stutter artifacts, and short amplicons, have improved human identification, kinship analysis, ancestry prediction, and mixture deconvolution capabilities. Information on published MHs,...
Topics
- Gene Frequency
- Genotype
- Haplotypes
- High-Throughput Nucleotide Sequencing
- Humans
- Polymorphism, Single Nucleotide