Article
Recurrent Alterations in the MAPK pathway in Sporadic Pyogenic Granuloma of Childhood.
Acta dermato-venereologica - 19 May 2022
Strobel Katharina, Maurus Katja, Hamm Henning, Roth Sabine, Goebeler Matthias, Rosenwald Andreas, Wobser Marion
Abstract excerpt
Pyogenic granuloma is one of the most common vascular tumours. The cause of pyogenic granuloma was previously thought to be an inflammatory reaction with consecutive stimulation of endothelial cell proliferation. However, recent studies suggest that pyogenic granuloma may be driven by constitutive activation of the mitogen-activated protein kinase pathway. The aim of this study was to investigate the molecular...
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