Article
HLA-DRB1∗16 and -DQB1∗05 alleles are strongly associated with autoimmune pancreatitis in a cohort of hundred patients.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 May 2022
Goni Elisabetta, Regel Ivonne, Mahajan Ujjwal Mukund, Amodio Antonio, De Marchi Giulia, Beyer Georg, Zuppardo Raffaella Alessia, Di Leo Milena, Lanzillotta Marco, Bonatti Francesco, Kauke Teresa, Dick Andrea, Weiss Frank Ulrich, Schönermarck Ulf, Lerch Markus M, Frulloni Luca, Cavestro Giulia Martina, Mayerle Julia
Abstract excerpt
BACKGROUND/OBJECTIVES: Autoimmune diseases are often associated with human leukocyte antigen (HLA) haplotypes, indicating that changes in major histocompatibility complex (MHC)-dependent self-peptide or antigen presentation contribute to autoimmunity. In our study, we aimed to investigate HLA alleles in a large European cohort of autoimmune pancreatitis (AIP) patients. METHODS: Hundred patients with AIP,...
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