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Article

Dental pulp stem cells as a promising model to study imprinting diseases

2 Apr 2022

Abstract excerpt

Parental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting diseases are characterized by growth and metabolic issues starting from birth to adulthood. They are mainly due to methylation defects in imprinting control region that drive the abnormal expression of imprinted genes. We currently lack relevant animal or cellular models...

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PMID: 35368018
DOI: 10.1038/s41368-022-00169-1

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