Article
SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes.
Microbiology spectrum - 27 Apr 2022
Martínez-González Brenda, Soria María Eugenia, Vázquez-Sirvent Lucía, Ferrer-Orta Cristina, Lobo-Vega Rebeca, Mínguez Pablo, de la Fuente Lorena, Llorens Carlos, Soriano Beatriz, Ramos Ricardo, Cortón Marta, López-Rodríguez Rosario, García-Crespo Carlos, Gallego Isabel, de Ávila Ana Isabel, Gómez Jordi, Enjuanes Luis, Salar-Vidal Llanos, Esteban Jaime, Fernandez-Roblas Ricardo, Gadea Ignacio, Ayuso Carmen, Ruíz-Hornillos Javier, Verdaguer Nuria, Domingo Esteban, Perales Celia
Abstract excerpt
Mutant spectra of RNA viruses are important to understand viral pathogenesis and response to selective pressures. There is a need to characterize the complexity of mutant spectra in coronaviruses sampled from infected patients. In particular, the possible relationship between SARS-CoV-2 mutant spectrum complexity and disease associations has not been established. In the present study, we report an ultradeep...
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