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MiR-106b-5p regulates esophageal squamous cell carcinoma progression by binding to HPGD

22 Mar 2022

Abstract excerpt

BACKGROUND: Several studies have documented the key role of microRNAs (miRNAs) in esophageal squamous cell carcinoma (ESCC). Although the expression of the 15-hydroxyprostaglandin dehydrogenase (HPGD) gene and miR-106b-5p are reportedly linked to cancer progression, their underlying mechanisms in ESCC remain unclear. METHODS: mRNA and miRNA expression in ESCC tissues and cells were analyzed using RT-qPCR....

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PMID: 35317779
DOI: 10.1186/s12885-022-09404-8

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