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Patterns of multiple congenital anomalies in the National Birth Defect Prevention Study: Challenges and insights

11 Mar 2022

Abstract excerpt

BACKGROUND: About 20%-30% of children with birth defects have multiple major birth defects in more than one organ system, often referred to as multiple congenital anomalies (MCAs). Evaluating the patterns of MCAs can provide clues to the underlying causes, pathogenic mechanisms, and developmental pathways. We sought to explore selected patterns of MCAs within the National Birth Defects Prevention Study (NBDPS), a...

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PMID: 35277952
DOI: 10.1002/bdr2.2003

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