Article
STARBOARD: encorafenib + binimetinib + pembrolizumab for first-line metastatic/unresectable BRAF V600-mutant melanoma.
Future oncology (London, England) - 1 Jun 2022
Schadendorf Dirk, Dummer Reinhard, Robert Caroline, Ribas Antoni, Sullivan Ryan J, Panella Timothy, McKean Meredith, Santos Edgardo S, Brill Kimberli, Polli Anna, Pietro Alessandra di, Ascierto Paolo A
Abstract excerpt
Despite the significant progress in the treatment of unresectable or metastatic BRAF V600-mutant melanoma, there remains two primary treatment options: targeted therapy and immunotherapy. Targeted therapy or immunotherapy alone is associated with efficacy limitations including efficacy limited to select patient subsets. With separate mechanisms of action and different response patterns, the combination of...
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