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Article

SGSM2 inhibits thyroid cancer progression by activating RAP1 and enhancing competitive RAS inhibition

9 Mar 2022

Abstract excerpt

Thyroid cancer (TC) is one of the most common malignancies involving the head and neck, and its incidences are increasing every year. Small G protein signaling modulators 2 (SGSM2) belongs to a newly identified protein group that contributes to numerous cancer progression. However, its role in TC remains unknown. The aim of this study was to explore the functions and underlying molecular mechanism of SGSM2 in the...

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PMID: 35264562
DOI: 10.1038/s41419-022-04598-y

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